lecture21_Cardio4

lecture21_Cardio4 - Cardiovascular Physiology IV...

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Cardiovascular Physiology IV Circulation and Blood Pressure (part 1) Reading : chapter 10, pgs 343-357
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Circulation and Blood Pressure - systemic and pulmonary circulation each consist of a closed system of vessels that transport blood to the tissues in parallel. C.O = 5 liters/min
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Arteries - composed of large vessels that carry blood from the heart. Arterioles - small diameter vessels that arise from the branching of arteries when they reach the organs they are supplying. Capillaries - the smallest diameter vessels that are formed when arterioles branch. Venules - the vessels that form when capillaries join together. Veins - large diameter vessels formed by the merging of venules. Microcirculation - the name given to the collection of arterioles, capillaries and venules. Basic Organization:
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Aorta Large Arterial Arterioles Capillaries Large Vena Cava Branches Veins feature 1 100’s ½ million 10 billion 100’s 2 internal radius number 1.25 cm .2 cm 30 µ m 3.5 µ m .5 cm 3 cm total cross- sectional area 4.5 cm 2 20 cm 2 400 cm 2 6,000 cm 2 40 cm 2 18 cm 2 Features of Blood Vessels
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Blood flow - determined by 1) the pressure gradient in the vessels, and, 2) the resistance to flow caused by friction and the viscosity of the blood. F = flow rate , volume of blood passing through a vessel per unit of time. P = pressure gradient , difference in pressure between the beginning and end of a vessel. R = resistance , resistance to flow depends on three factors: 1) blood viscosity - friction developed in blood, determined by the concentration of plasma proteins, and the number
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lecture21_Cardio4 - Cardiovascular Physiology IV...

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