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Study Questions 1

Study Questions 1 - NPB 100 Neurobiology Winter 2011 STUDY...

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NPB 100 Neurobiology Winter 2011 STUDY QUESTIONS 1. What is ionic selectivity? How do voltage-gated channels, ligand-gated channels, and gap junctions differ in their selectivities, and how are these differences related to their molecular structures? 2. During an action potential, the membrane's Na + -channels open and Na + ions enter the cell. What effect does this Na + influx have on the concentration of Na + inside the neuron? Explain why this is so. 3. What is reciprocal inhibition? What is lateral inhibition? How do these forms of synaptic organization differ? 4. What features of a good patch-clamp system permit it to resolve the currents that flow through single channels? 5. "Space-constant" and "time-constant" are parameters that can be measured, and used to describe the passive spread of potentials in neurons. What is "passive spread"? How are these two constants relevant to passive spread, and why is this so? Under what conditions do these parameters fail to describe the spread of potentials in neurons?
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