Lecture 4 - How Can Voles Be Useful ± Prairie Voles ±...

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Biological Processes PSY 12000: Fall 2011 Purdue University Eric D. Wesselmann, Ph.D. 2 Overview Brain Structure and Neuroscience Physiology and Psychology overlap Neurotransmitters and Mental Health 3 Guest Speaker Ashley Martin Department of Psychological Sciences Purdue University Example: Using Animal Models Study several behaviors in the prairie voles related to depression and other mood disorders. Study the effects of social situations on brain cells and the Central Nervous System. Analyze hormones and chemicals associated with stress, behavior, emotion, and cardiovascular function. 5 Prairie Voles (Microtus ochrogaster)
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Unformatted text preview: How Can Voles Be Useful? ± Prairie Voles: ± Form social bonds ± Most mate monogamously ± Show sensitivity to social stressors ± Chronic stress manipulation: 4 weeks of isolation from mate ± Can do various surgical procedures we cant do on human subjects 6 How Do Voles Respond to Chronic Stressors? ± Increased resting heart rate; exaggerated cardiac response to acute stress ± Increased corticosterone (akin to cortisol) ± Behaviors that mimic depression in humans ± Anhedonia ± Learned helplessness ± Behaviors that mimic anxiety ± Oxytocin reduces these effects 7...
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