310_27 - CH 310 N LECTURE 27 Textbook Assignment: Chapter...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
CH 310 N LECTURE 27 Textbook Assignment: Chapter 26-Lipids Homework (for credit): HW 10 Today’s Topics: Lipids-structure; classification Notice & Announcements:
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Steroids: Steroids: a group of plant and animal lipids that have this tetracyclic ring structure: • The features common to the ring system of most naturally occurring steroids are: AB CD Steroids – the fusion of rings is trans and each atom or group at a ring junction is axial – the pattern of atoms or groups along the ring junctions is nearly always trans -anti- trans - anti- trans H CH 3 H H CH 3 H Steroids
Background image of page 2
glucocorticoid hormones (e.g., cortisone) mineralocorticoid hormones (e.g., aldosterone) sex hormones (e.g., testosterone and estrone) bile acids (e.g., cholic acid) cholesterol Cholesterol is the Cholesterol is the Precursor for Families of Precursor for Families of Steroids Steroids Cholesterol H 3 C HO H 3 C H H H
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Biosynthesis of Steroids The building block from which all carbon atoms of steroids are derived is the two carbon acetyl group of acetyl-CoA- Stage 1: Stage 1: synthesis of isopentenyl pyrophosphate from three molecules of acetyl-CoA Stage 2: Stage 2: synthesis of cholesterol Stage 3: Stage 3: conversion of cholesterol to other steroids glucocorticoid hormones (e.g., cortisone) mineralocorticoid hormones (e.g., aldosterone) sex hormones (e.g., testosterone and estrone) bile acids (e.g., cholic acid) cholesterol CH 3 -C-S-CoA O Acetyl Coenzyme A Isopentenyl pyrophosphate (R)-Mevalonate (C 10 ) 15 ) Geranyl pyrophosphate Farnesyl pyrophosphate 30 ) Squalene C 10 terpenes C 15 and C 20 terpenes C 30 terpenes OH HO CH 3 O - O OP 2 O 6 3- Cholesterol Biosynthesis of Cholesterol Details
Background image of page 4
Geranyl pyrophosphate Isopentenyl
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 17

310_27 - CH 310 N LECTURE 27 Textbook Assignment: Chapter...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online