08_lecture - Chapter 8 Control of Microorganisms in the...

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Unformatted text preview: Chapter 8 Control of Microorganisms in the Environment 1 2 Figure 8.1 sterilization destruction or removal of all viable organisms disinfection killing, inhibition, or removal of disease causing (pathogenic) organisms disinfectants agents, usually chemical, used for disinfection usually used on inanimate objects 3 Definition of Frequently Used Terms sanitization reduction of microbial population to levels deemed safe (based on public health standards) antisepsis prevention of infection of living tissue by microorganisms antiseptics chemical agents that kill or inhibit growth of microorganisms when applied to tissue 4 More Definitions 5 Figure 8.2 chemotherapy use of chemicals to kill or inhibit growth of microorganisms within host tissue agents that kill microorganisms or inhibit their growth cidal agents kill static agents inhibit growth 6 Antimicrobial Agents- cide suffix indicating that agent kills germicide kills pathogens and many nonpathogens but not necessarily endospores include bactericides, fungicides, algicides, and viricides 7-cidal Agents- static suffix indicating that agent inhibits growth include bacteriostatic and fungistatic 8-static Agents 9 The Pattern of Microbial Death microorganisms are not killed instantly population death usually occurs exponentially measure of agents killing efficiency decimal reduction time time to kill 90% must be sure persister cells (viable but nonculturable (VBNC) condition) are dead once they recover they may regain the ability to reproduce and cause infection 10 Figure 8.3 The Pattern of Microbial Death population size larger populations take longer to kill than smaller populations population composition microorganisms differ markedly in their sensitivity to antimicrobial agents 11 Conditions Influencing the Effectiveness of Antimicrobial Agent Activity concentration or intensity of an antimicrobial agent usually higher concentrations or intensities kill more rapidly relationship is not linear duration of exposure longer exposure Þ more organisms killed 12 More Conditions...
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This note was uploaded on 02/04/2012 for the course BIO 326R taught by Professor Whiteley during the Spring '08 term at University of Texas at Austin.

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08_lecture - Chapter 8 Control of Microorganisms in the...

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