32 - Hormonal Control - Hormonal Control of Metabolism...

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Hormonal Control of Metabolism ! Intracellular signal transduction pathways ! Receptor protein kinases ! Growth hormones, oncogenes and cancer L e arning Obj ec t iv s
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Fig 13-12 Signal Transduction ! Endocrine glands synthesize and release hormones, which are carried by the bloodstream to the target cells. ! Example hormones: insulin, glucagon, catecholamines, steroids. ! Metabolic processes of the organism are under strict hormonal and neuronal control.
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Signal Transduction ! A hormone or neurotransmitter may affect biochemical reactions within a cell only if the cell has a corresponding receptor for the signal. ! A typical cell has receptors for many signaling molecules. Response to a particular signal depends on whether and how the signal transduction pathway reacts to other signals. ! The receptor activation initiates reactions in a s ignal tran s du c tion pathway that triggers the cell response.
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First Messengers
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Second Messengers
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Receptor Tyrosine Kinases (RTKs) !
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32 - Hormonal Control - Hormonal Control of Metabolism...

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