11 - Sleep states alter activity of SCN neurons, Deboer

11 - Sleep states alter activity of SCN neurons, Deboer -...

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Article #11 Sleep States Alter Activity of Suprachiasmatic Nucleus Neurons Abstract: Timing of sleep and wakefulness is governed by a sleep homeostatic process and by the circadian clock of the SCN which has a molecular basis for rhythm generation Changes in vigilance states are correlated with SCN electrophysiological activity During REM sleep SCN activity is higher than during non-REM sleep Changes in SCN electrical activity are caused by changes in vigilance state 24 hour electrical activity is controlled by the molecular machinery of the SCN is substantially modified by afferent information from the central nervous system Intro: Functions of sleep: memory function, brain energy metabolism, and genetic programming Sleep and wakefulness are regulated by two processes: a sleep homeostatic process that increases during waking and decreases during sleep, and a circadian process that provides the sleep homeostat with a circadian framework. Slow wave activity (SWA) (in the EEG range of 1-4Hz) reflects the status of the
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This note was uploaded on 02/05/2012 for the course BIOLOGY 3u3 taught by Professor Dr.rollo during the Spring '11 term at McMaster University.

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11 - Sleep states alter activity of SCN neurons, Deboer -...

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