Lecture 5- January 23

Lecture 5- January 23 - DNA replication Reading: Chapter 4,...

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DNA replication Reading: Chapter 4, pp65-66 14.2-14.4 Outline: I.DNA forms the template for it’s own synthesis II.The Meselson-Stahl experiment: DNA synthesis is semi- conservative III.DNA replication – the process and the players IV.Leading vs. lagging strand V.Synthesis of the Lagging Strand VI.Prokaryotes vs. Eukaryotes VII.Replicating the Ends of Linear Chromosomes
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I. DNA forms the template for it’s own synthesis
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II. The Meselson-Stahl experiment: DNA synthesis is semi-conservative A. 3. 2. 1.
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Matthew Meselson Franklin Stahl II. The Meselson-Stahl experiment: DNA synthesis is semi-conservative B. The experiment
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II. The Meselson-Stahl experiment: DNA synthesis is semi-conservative B. The predictions
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II. The Meselson-Stahl experiment: DNA synthesis is semi-conservative B. The Results!
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III. DNA replication – the process A.
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B. Step 1 - 1. Helicase- 2. Single-strand DNA binding proteins- 3. DNA unwinds at the Replication Fork – 4. Stress is relieved by-
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5. Primase- lay down RNA primer to provide a free 3’ OH group for the next step…
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Lecture 5- January 23 - DNA replication Reading: Chapter 4,...

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