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Exam III fall 03 - -~ BI0321 Exam 3 Fall 2003 Page 1 of 4'v...

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(. -~ .".. ,..,,"". BI0321 Exam 3 Fall 2003 Page 1 of 4 ... ,.,., "" 'v"".. ~.-,", ,.-. .,~.M.'," .,. "..,-, ..". ' '.- ~'-"-"~' ._' W'o,'..' ..'; ,,' ',-" '\.'; 1.Which of the following classes of molecule that form the cytoskeleton produce the strongest filaments? ~A.actin filaments B.microtubules C--.rj,.nt.c r ll1t::H] i a -t e £ 1.1en'i\ent--s- 2.At wha.t stage of mitosisare seen to start to condense? A.Anaphase B.Telophase <C.iProphase D.S phase 3.There are 5 types of histone proteins, called aI, H2, H3, H4 and HS A.True ~B.False chromosomes lPrv1AP 4.In eucaryotes, all genome is required expression A.True -B. False of the DNA in the for normal gene 5.General transcription factors activate transcription in both procaryotes and eucaryotes -<A.True B.False gene -' -6.How many levels of chromatin there in eucaryotes? A.I B.2 '"C.3 . D.more than 3 packing are ..7. RNA processing is a form of gene control -A. True B.False -a. Gender in Drosophilia embryos is defined by the genes sex-lethal, transformed and double-sex. Interplay between these gene products result in the formation of the same type of protein. How can this same type of protein define both sexes? ~A.it depends on the amount of protein produced B.the protein is the product of regulated alternative splicing ~.the protein binds to other variable factors in cells of the germ line 9.Checkpoints in the cell cycle are controlled by binding of proteins to cyclin-cdk complexes A.True S.False --- ~O.Which of the following classes of that form the cytoskeleton has a cylindrical structure? A.actin filaments .,..,B .microtubules C.intermediate filaments molecule ~l.Why does cyclin concentration rise and fall with the cell cycle but cdks do not? A.cyclins are degraded after the cyclin- cdk complex becomes active B.the production of cyclin mRNA is switched on and off at different times in the cell cycle C.cyclins, but not cdks, are inhibited by CAK D.cdks',but not cyclins, are inhibi.ted by CA.-I< \ 12.What role does the ARP complex play in cell movement? A.the c~plex ~cts * a ~ cleati~ si~e for ,ubUI~:\mono ers in the l~adi~g edge of the cell cort x ~.the complex acts as a nucleation site for actin monomers in the leading edge of the cell cortex C.the co ~ ex.ac ~ as a ~ ~clea\ion ~f7e for t ulln m Domer ~n the\traJ.~ng edge 0 the ce 1 core~x D.the complex acts as a nucleation site for actin monomers in the trailing edge of the cell cortex --13.What is the connection between profilin and thymosin? -A. they regulate the polymerization of actin B.they regulate the polymerization of intermediate filaments c. -they control ATP hydrolysis by tubulin in the polymerized form --i.4.Whatis meant by combinatorial gene control?
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