TEST 3 - CHE 330-01 Exam #3 April 16th, 2010 This...

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1 CHE 330-01 Exam #3 April 16th, 2010 This examination is worth 100 points. Please mark (bubble) your answer on the sheet provided. GOOD LUCK ---------------------------------------------------------------- Multiple Choice: (3.5 points each) 1. Calculate the isoelectric point (pI) of the peptide below. E-A-R-L a. 6.1 b. 7.0 c. 11.1 d. 8.4 e. 4.8 2. The peptide below underwent reaction with methanol to convert all carboxylic acid groups to methyl esters. Calculate the net charge on the modified peptide at pH = 6.3. D-R-E-A-M a. 0 b. -1 c. -2 d. +1 e. +2 3. Which of the following molecules (which are roughly the same size), will be the MOST soluble in water? a. 1-Propanal b. Dimethylketone c. Ethylmethylether d. Butane e. 1-Propanol 4. The p K a of the side chain of Glu-35, which acted as a general acid in the first step of the mechanism of Lysozyme, had a _____ than typical p K a value (compared to the value for the free amino acid) because it is ______________________________. a. higher; in a nonpolar environment b. higher; near a metal ion c. higher; near basic AA side chains d. lower; in a nonpolar environment e. lower, near a metal ion 5. Which of the following statements is TRUE? a. A Lys side chain in a protein will have a lower p K a when surrounded by metal ions than when it is surrounded by water b. The p K a of amino acid side chains in proteins do not depend on their environment c. An aspartic acid side chain in a protein will have a higher p K a when surrounded by metal ions than when it is surrounded by water d. The amino acid M will have a side chain p K a when incorporated into a protein e. At pH = 11, the major form of Tyr side chains will have a positive charge 6. Which of the following is NOT an alcohol that can be a component of a glycerophospholipid? a.
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This note was uploaded on 02/05/2012 for the course CHE CHE 330 taught by Professor Dr.c during the Spring '11 term at Murray State KY.

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TEST 3 - CHE 330-01 Exam #3 April 16th, 2010 This...

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