ExtraCreditHomework11KEY - Name: KEY EID: Extra Credit...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Name: KEY EID: Extra Credit Homework #11 Complete the questions below and hand in to a TA by the end of class, Wed., Nov. 30. 1. Describe the consequences (i.e. what will be inhibited and what will function) of the following inhibitors of oxidative phosphorylation in mitochondria. a) Dinitrophenol (DNP) DNP abolishes the proton gradient by transporting protons across the mitochondrial membrane. Therefore, oxidation can continue, but synthesis of ATP cannot. b) Cyanide Cyanide inhibits cytochrome oxidase (Complex IV) by binding in place of O 2 Without the transfer of electrons there is neither oxidation nor phosphorylation. c) Oligomycin Oligomycin inhibits ATP synthase. Without ATP synthesis, oxidation halts as well. d) Bongkrek acid Bongkrek acid interferes with the ATP/ADP translocation mechanism, preventing ATP from leaving the mitochondrion and providing energy to the cell. Since ATP cannot be produced, oxidation also halts. 2. Surprisingly, the
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 2

ExtraCreditHomework11KEY - Name: KEY EID: Extra Credit...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online