Bloodline - Bloodline Human Genetics and Pedigrees*Based on the CBS show Ghost Whisperer Season 4 episode 5"Bloodline Original Airdate October 31st

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1 Bloodline* Human Genetics and Pedigrees *Based on the CBS show, Ghost Whisperer , Season 4, episode 5 “Bloodline”. Original Airdate: October 31st, 2008 http://www.yidio.com/show/ghost-whisperer/season-4/episode-5/22854
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Learning Objectives 1. Given parental genotypes, be able to identify the possible gametes and make Punnett squares to determine the genotypic and phenotypic ratios of predicted offspring. 2. Construct pedigrees and be able to distinguish patterns of inheritance seen in pedigrees such as the differences between autosomal and sex-linked and recessive and dominant patterns of inheritance. 3. Use pedigree analysis to develop a hypothesis for how a certain disease in transmitted. 4. Weigh evidence such as a pedigree chart or incomplete transmission to determine the probability that an individual will develop a certain disease.
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3 Questions What do you think is going on with these two families? The hospital would have simple things like Diana’s blood type on file. How could you use blood type to figure out what is going on?
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4 Olivia’s parents, Mrs. Lisa Keller and Mr. Kevin Keller, are (A-) and (O+). You know about the IA/IB/i alleles for ABO blood type and the Rh D factor alleles, +/-. Write down all possible genotypes for Lisa and Kevin Keller and use them to create several Punnett squares to indicate the possible genotypes for their offspring. Olivia has O- blood. Using your Punnett Squares and the phenotypes of the three Kellers, indicate which of the following is the most likely set of genotypes for Lisa and Kevin Keller? Lisa Kevin A. IA / i, -/-i / i, +/+ B. IA / IA, -/- i / i, +/- C. IA / i, -/-i / i, +/- D. IA / IA, -/- i / i, +/+ Clicker Question 1
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Looking at the Kellers and Morrisons, is it possible that Kevin Keller had an affair with Cynthia Morrison and is Diana Morrison’s biological father? Lisa Keller Kevin Keller Cynthia Morrison Mr. Morrison A- O+ B+ O- Olivia Keller Diana Morrison O- A+ A. Yes, Cynthia and Kevin could have a child like Diana with Rh positive blood. B. No, Cynthia and Kevin could not have a child who has type A blood. C. No, Cynthia and Kevin could not have a child who was Rh positive. Before we go to the next slide, what other problem do you see?
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This note was uploaded on 02/07/2012 for the course BIOL 1103 taught by Professor Armstrong during the Fall '07 term at University of Georgia Athens.

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Bloodline - Bloodline Human Genetics and Pedigrees*Based on the CBS show Ghost Whisperer Season 4 episode 5"Bloodline Original Airdate October 31st

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