Lecture_20Spring09

Lecture_20Spring09 - CHM 115 Lecture 20 (03-31-09)...

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1 CHM 115 Lecture 20 (03-31-09) Biochemistry
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2 Amino Acids The basic structure of an amino acid carboxylic acid amine amine R = one of 20 different “side groups”
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3 Question #1 Which of these represents a peptide bond? Choice A Choice B Choice C Choice D
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4 Physiological Form of Amino Acids At physiological pH inside the cell, the amino acids exist in their ionized form. This is referred to as a zwitterion, having two opposite charges on the same molecule.
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5 Amino Acids: Non-polar Side Chains
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6 Amino Acids: Polar Side-chains
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7 Ionic Side Chains acidic acidic basic basic
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8 Question #2 Which amino acid is most likely to be found on the outside of a protein that will be in an aqueous environment? A. Leu B.Ser C.Phe
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9 Peptide Bonds Amino acids link together through a “peptide bond” Two amino acids dipeptide Many amino acids polypeptide Amide group
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10 Proteins Can range in size from about 50 to several thousand amino acids. Can have one or several separate polypeptide chains held together. Amino acid sequence determines shape and shape determines function .
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11 Structure of Proteins Primary : sequence of amino acids
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12 Structure of Proteins Primary : sequence of amino acids Secondary : spatial arrangement of the polypeptide into shapes such as sheets or helices
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Lecture_20Spring09 - CHM 115 Lecture 20 (03-31-09)...

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