Homework 5 Solutions

# Homework 5 Solutions - Question Imagine you are studying a...

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Question Imagine you are studying a cell resting at EL = -70mV, with a 1nS leak conductance, and 10pF membrane capacitance. At t=0, marking the beginning of period 1 (P1), a 9nS Na+ conductance is activated. Assume ENa = +50mV. After 1ms, the sodium conductance returns to 0 and a potassium conductance gK=15nS is activated. Call that the beginning of period P2. You are interested in what the membrane potential will be 2ms later, that is, 2ms into P2. You will be asked to give all the intermediate calculations of Vstart, A, D, tau, and Vfinal for each period. First question, what is the starting voltage at the beginning of P1? Give answer in mV, accurate to 0.01. Answer -70 Question Continuing from above, what is A (sometimes called Vinfinity) during P1? Give answer in mV acccurate to 0.01. Answer 38 Question What is D (i.e. the decaying part of the exponential) during P1? (answer in mV) Answer -108 Question What is tau during P1? (in ms, to 0.01 accuracy) Answer 1 Question What is Vm at t=1ms, i.e. at the end of P1? (answer in mV) Answer -1.731 Question What is A during P2? (in mV)

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