1stMidt Study Guide_Spring2012

1stMidt Study Guide_Spring2012 - 1st Midterm Exam; Tuesday...

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Unformatted text preview: 1st Midterm Exam; Tuesday February 21, 2012 Exam will consist of various forms of multiple choice questions; best single answer or combination of answers (see samples on next page). Total of 50 points for the exam. You will need a Scantron 882-ES Topics to be covered: Cells and Organs of the Immune system Innate and adaptive immunity Cellular Interactions in the immune system Antibody structure and antigens Which of the following manipulations can provide "passive immunity" ? A. Injection of inactivated virus B. Injection of immune serum C. Blood transfusion with the wrong blood type D. Transplantation of incompatible skin graft E. None of the above Example of type 1 question: Answer: B __C ___ Antibodies are 1. types of cells that protect the body from pathogens 2. the antigen receptors on B cells 3. viruses that cause disease 4. responsible for the transfer of passive immunity Example of type 2 question: A, if 1, 2, 3 are correct B, if 1 and 3 are correct C, if 2 and 4 are correct D, if only 4 is correct E, if all are correct In the following pages the first page lists a question and the page that follows lists the answer to that question Name as many differences as you can between Innate and Adaptive Immunity Comparison of the features between Innate and Adaptive Immunity Highly specific, multiple genes recombining during development Fixed in genome, few genes recognize molecular patterns Receptors and Diversity T and B cells, APC Phagocytic cells Cell types Cytokines, Antibodies Cytokines, anti-microbial peptides, costim molecules Products Response improves upon repeated exposure No memory, response is the same every time Memory Takes time. It improves upon repeated exposure Fast, same kinetics upon repeated exposure Time kinetics Imperfect. Cells recognizing host must be selected out Do not recognize host molecules Self, non-self discrimination Recognize molecular details Recognize conserved patterns of microbial molecules Recognition and Specificity Clonal, each cell slightly different receptors Non-clonal, all cells same receptor Distribution Adaptive Innate Property Give one example of an Innate Immune Response and one example of an Adaptive Immune Response Innate Release of pharmacological compounds from epithelial cells (vasoactive, chemotactic) Complement activation through C3 (alternative) Adaptive Production of antibodies Production of cytokines What is the name of the tertiary structure that is composed of two layers of antiparallel beta strands (beta sheets) connected with a disulfide bond ? Immunoglobulin (Ig) domain or fold. This kind of structural pattern (motif) is characteristic of both BCR (antibody) and TCR, as well as some other proteins related to the immune system What is the difference between Active Immunity and Passive Immunity?Passive Immunity?...
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This note was uploaded on 02/09/2012 for the course MUSI 109 taught by Professor Chan during the Spring '10 term at Miramar College.

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1stMidt Study Guide_Spring2012 - 1st Midterm Exam; Tuesday...

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