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Week 3b ADHD2(1)

Week 3b ADHD2(1) - ADHD Part Two Theories of etiology and...

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Unformatted text preview: ADHD: Part Two Theories of etiology and maintenance Biological diatheses? Environmental stress? Developmental model Treatment Overview of treatment approaches MTA study MTA treatments MTA results Genetic risk Biological Diatheses? Genetic risk – Parent to child transmission (60% rate) – Twin studies (65% concordant; 80% heritability estimate) – Few specific genes located (DRD4) – Likely a multi-gene problem Biological Diatheses? Genetic risk – Parent to child transmission (60% rate) – Twin studies (65% concordant; 80% heritability estimate) – Few specific genes located (DRD4) – Likely a multi-gene problem Neurobiological correlates – Prefrontal abnormalities (underactive, delay in growth) – Basal ganglia abnormalities (lesion data) – Dopamine dysregulation Biological Diatheses? ADHD: Part Two Theories of etiology and maintenance Biological diatheses? Environmental stress? Developmental model Treatment Overview of treatment approaches MTA study MTA treatments MTA results Pregnancy and birth – Prenatal substance exposure (smoking) – Low birth weight / malnutrition Environmental Stress? Pregnancy and birth – Prenatal substance exposure (smoking) – Low birth weight / malnutrition Postnatal toxins – Lead paint and pipes – Sugar and food additives – Allergens Environmental Stress? Pregnancy and birth – Prenatal substance exposure (smoking) – Low birth weight / malnutrition Postnatal toxins – Lead paint and pipes – Sugar and food additives – Allergens – NO strong support for toxin hypotheses Environmental Stress? Pregnancy and birth – Prenatal substance exposure (smoking) – Low birth weight / malnutrition Postnatal toxins – Lead paint and pipes...
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Week 3b ADHD2(1) - ADHD Part Two Theories of etiology and...

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