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edema2 - Dr.ManalGabril Assistantprofessor...

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Dr. Manal Gabril Assistant professor Pathology, LHSC, University Campus
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Blood flow- normal fluid homeostasis Edema Hyperemia Hemorrhage Maintenance of blood as a liquid Thrombosis Embolism Infarct Shock
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Both indicate a local increased volume of blood in  a particular tissue.
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Dilatation of arteries/arterioles results in increased  blood flow (perfusion) of a tissue or organ 
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The tissue appears red. Because of engorgement with oxygenated blood  Example:  “redness” of acute inflammation due to hyperemia. Skeletal muscle during exercise
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Impaired venous drainage results in stasis and the  accumulation of deoxygenated blood Due to increase in venous hydrostatic pressure   
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The tissue has a bluish tinge due to the  accumulation of deoxygenated hemoglobin  Examples: Cardiac failure Isolated venous obstruction Thrombophlebitis   
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Chronic dilated, congested central veins-> necrosis (dark spots) unaffected surrounding liver tissue (pale spots).
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A consequence of tightly regulated processes that  maintain blood in a fluid , clot-free state in normal  vessels The pathologic form of hemostasis is thrombosis
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Blood   fluid state depends on: Integrity of vessels (vascular wall) Normal blood flow Normal blood viscosity  Normal blood composition (Platelets and coagulation  factors)
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Formation of mass/clotted blood in the heart or  blood vessels
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