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Unformatted text preview: BIOST / EPI 513 Spring Quarter 2011 Dr. McKnight HOMEWORK 3 Due in the class online drop box at 9pm, Monday, April 18, 2011 Please do not turn in any computer output. 1. In a matched case-control study of risk factors for benign breast disease (BBD), investigators were interested in whether a woman had given birth a ff ected her risk of the disease. Cases were women diagnosed with fibrocystic benign breast disease; for each case, an age-matched control was identified from women admitted for general surgery, orthopedic or otolaryngologic services to the same hospital as the case. The numbers of cases and matched controls who had and had not ever given birth are given in the table below. Controls Cases 1 Birth No Births Total 1 Birth 9 16 25 No Births 9 16 25 Total 18 32 50 (a) The first part of this question asks you to analyze these data adjusting for the matching. Using methods appropriate for matched pairs, please provide: i. An estimate of the OR for the association between having had 1 birth and BBD. ii. A 95% Confidence Interval for this OR....
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- Spring '11