Lecture 10 – Membrane Proteins

Lecture 10 – Membrane Proteins - group...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Topic 8 – Membrane Proteins (Lecture 10) The composition of a membrane (by mass) is the following: about 50% lipids,  about 50% proteins and about 1-2% carbohydrates.  The fluid mosaic model describes how proteins are free to diffuse laterally within  the bilayer unless movement is restricted by cellular components.  Membrane proteins  have the following  functions:  transporters,  anchors, receptors and  enzymes.  There are 4 types of membrane proteins: transmembrane,  monolayer-associated, lipid linked and protein attached. The last is a peripheral  membrane protein. Transmembrane proteins are exposed to both sides and are always alpha helical in  structure. This maximizes the hydrogen bonding between the polar backbone 
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: group minimizing the interaction between the hydrophobic interior. There are about 20 amino acids that’s span the bilayer. This is an integral membrane protein. • Monoassociated proteins only span one side of the bilayer. The hydrophobic part is embedded into the layer. • Lipid linked are proteins that are covalently bonded to lipids in the membrane. It is usually covalently bonded to cysteine. • Because protein attached are peripheral membrane proteins, it is easier to study because you just need to break the interaction between the transmembrane protein and the attached protein....
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online