BioInfoSyl

BioInfoSyl - Prerequisite : Programming knowledge, Discrete...

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CSE 5615 Computational Molecular Biology Instructor : Debasis Mitra, Room : Harris 325 Since the days when DNA was found to be comprised of four letters a , t , c , and g , “life” is showing its digital face. Life seems to be partly biology and partly computing, and for the same reason computer is becoming more and more important instrument for doing biology, particularly molecular biology. In this course we will introduce some important computational problems and algorithms related to molecular biology. The students are expected to have programming skill. Interested non-computer science students should contact the instructor first. Necessary introduction on biology will also be provided . No prerequisite in Biology is expected.
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Unformatted text preview: Prerequisite : Programming knowledge, Discrete Mathematics, Data structures. Sample Topics: Motif finding (functional components of protein) Approximate Sequence Alignment (gene finding on DNA) Shortest superstring finding (DNA sequencing) Protein structure comparison (what may a newly found gene do) Protein-ligand binding (useful for drug discovery) Text : An Introduction to Bioinformatics Algorithms , by Neil Jones and Pavel Pevezner, The MIT Press, 2004, 0-262-10106-8. Evaluation : Class participation, Programming assignments, Presentations, Project Other Important Information on the Class Web Page: http://www.cs.fit.edu/~dmitra/Compbio/...
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