MolBioBackground

MolBioBackground - Molecular Biology Background Debasis...

Info iconThis preview shows pages 1–15. Sign up to view the full content.

View Full Document Right Arrow Icon
02/10/12 dmitra 1 Molecular Biology Background Debasis Mitra Florida Tech Credit: Pevezner text-site
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 2 Section1: What is Life made of?
Background image of page 2
02/10/12 dmitra 3 2 types of cells: Prokaryotes v.s.Eukaryotes
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 4 Life begins with Cell A cell is a smallest structural unit of an organism that is capable of independent functioning All cells have some common features
Background image of page 4
02/10/12 dmitra 5 Prokaryotes and Eukaryotes •According to the most recent evidence, there are three main branches to the tree of  life.  •Prokaryotes include Archaea (“ancient ones”) and bacteria. •Eukaryotes are kingdom Eukarya and includes plants, animals, fungi and certain  algae.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 6 Prokaryotes and Eukaryotes, continued Prokaryotes Eukaryotes Single cell Single or multi cell No nucleus Nucleus No organelles Organelles One piece of circular DNA Chromosomes No mRNA post transcriptional modification Exons/Introns splicing
Background image of page 6
02/10/12 dmitra 7 Overview of organizations of life Nucleus = library Chromosomes = bookshelves Genes = books Almost every cell in an organism contains the same libraries and the same sets of books. Books represent all the information (DNA) that every cell in the body needs so it can grow and carry out its vaious functions.
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 8 Chromos omes Organism Number of base pair number of Chromosomes --------------------------------------------------------------------------------------------------------- Prokayotic Escherichia coli (bacterium) 4x10 6 1 Eukaryotic Saccharomyces cerevisiae (yeast) 1.35x10 7 17 Drosophila melanogaster(insect) 1.65x10 8 4 Homo sapiens(human) 2.9x10 9 23 Zea mays(corn) 5.0x10 9 10
Background image of page 8
02/10/12 dmitra 9 Bio-molecules Nucleic acids (DNA, RNA): Library of life Proteins: Workhorse of life Fatty acids, carbohydrates, and other supporting molecules
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 10 DNA DNA has a double helix structure which composed of sugar molecule phosphate group and a base (A,C,G,T) DNA always reads from 5’ end to 3’ end for transcription replication 5’ ATTTAGGCC 3’ 3’ TAAATCCGG 5’
Background image of page 10
02/10/12 dmitra 11 DNA, RNA, and the Flow of Information Translation Transcription Replication
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 12 Proteins Functions Structural Enzymes Information exchange (e.g., across cell walls) Transporting other molecules (e.g., oxygen to cells) Activating-deactivating genes Etc.
Background image of page 12
02/10/12 dmitra 13 Proteins Amino acids Protein is a chain of “residues” 20 to 5000 long, typically a few hundred long
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
02/10/12 dmitra 14 Protein structure Important for its function Primary structure: sequence Secondary structure: a few topological features Tertiary structure: 3D folding Quaternary structure: Protein complex
Background image of page 14
Image of page 15
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/10/2012 for the course CSE 5615 taught by Professor Mitra during the Fall '11 term at FIT.

Page1 / 46

MolBioBackground - Molecular Biology Background Debasis...

This preview shows document pages 1 - 15. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online