Muscle I

Muscle I - Muscle I 1 Lecture Outline Functions of Skeletal...

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Muscle I 1
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Lecture Outline Functions of Skeletal Muscle Structural Hierarchy of Muscle Sarcomere Structure Thick Filaments – myosin Thin filaments – actin, troponin and tropomyosin Sliding Filaments and Cross-bridge Cycling Neuromuscular Junction and Causes of Muscle Contraction Force Production in Skeletal Muscle Single Muscle Fibers Whole Muscles 2
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Functions of Skeletal Muscles Produce skeletal movement Maintain body position Support soft tissues Guard openings Maintain body temperature Store nutrient reserves 3
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Sarcomere Structure 6
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A cross section through a sarcomere shows that: • each myosin can interact with 6 actin filaments, and • each actin can interact with 3 myosin filaments. 7
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Myosin & Thick Filaments 8
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Thin Filament Structure 10
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Sliding Filament Theory 12
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Neuromuscular Junction 17
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Thought Questions What would be the effect of excess Calcium on the inside of the muscle cell? What would be the effect of a lack of ATP in a cell with excess calcium? What is the name of this condition?
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This note was uploaded on 02/09/2012 for the course BIO 102 taught by Professor William during the Spring '11 term at Harvard.

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Muscle I - Muscle I 1 Lecture Outline Functions of Skeletal...

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