Homework_3 - Assessment Page 1 of 3 1. Acetaminophen is...

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1. Acetaminophen is metabolized by the following Phase I enzyme: A) Glucuronyl transferase B) CYP2E1 C) CYP3A4 D) None of the above 2. The increased hepatic expression of CYP450 is called: A) Inhibition B) Induction C) Phase I reaction D) Phase II reaction 3. The irreversible lesions that are characteristic of cirrhosis result from deposition of __________ by fibroblasts. A) Epithelial cells B) Lipids C) Bile acids D) Collagen 4. The highest concentration of CYP450 enzyme in the liver are found in: A) Zone 1 B) Zone 2 C) Zone 3 D) Zone 4 5. The reactive intermediate formed when acetaminophen undergoes Phase I metabolism is: A) NAPQI B) Isoniazid C) CYP2E1 D) APAP 6. The blood vessel that brings blood directly from the GI tract to the liver is the: A) portal vein B) Hepatic artery C) Central vein D) Bile duct 7. Phase II reactions are typically _________ reactions. A) Oxidation B) Reduction C) Conjugation D) Idiosyncratic 8. Ethanol is thought to cause steatosis by: A) Increasing lipid production B) Preventing lipid breakdown
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This note was uploaded on 02/10/2012 for the course JAPANESE 102 taught by Professor Sensei during the Spring '11 term at Alabama.

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Homework_3 - Assessment Page 1 of 3 1. Acetaminophen is...

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