Week_11_-_Learning_objectives___assignme -...

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Learning objectives: Describe fundamental differences between the different cells of the nervous system, and between the autonomic and central nervous systems Understand basic principles of neurotransmission, including neurotransmitters, synapses and electrical conduction Describe the blood-brain barrier and list the properties that make it impermeable to most toxicants Understand how toxicant interactions with ion channels and enzymes can lead to toxicity Identify the specific mechanisms underlying toxicity of tetrodotoxin (TTX),
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Unformatted text preview: batrachotoxin (BTX), cocaine, triethyltin (TET), organophosphate pesticides, botulinum toxin, MPTP, isoniazid, methylmercury, ecstasy (MDMA) Describe the advantages and disadvantages of specific in vivo and in vitro assays for measuring neurotoxicity Required reading: Casarett & Doull: Chapter 16 (p. 217-231) Suggested additional reading: Berne & Levy: Chapters 3, 4 and 6 Assignments: 1) Review Week 11 lecture content 2) Homework #4 – due 7/31/2011 (submission “quiz” is available in Week 11 folder)...
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