Unit5 - Unit 5 1 UNIT 5 MEMBRANES AND MEMBRANE PROTEINS...

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Unit 5 1 U NIT 5 M EMBRANES AND M EMBRANE P ROTEINS Note: The test for this unit is combined with the test for Unit 4. Membranes define the external boundary of cells and regulate it's molecular traffic. They divide the internal space of the cell into discrete compartments. Membranes are not merely passive barriers but house an array of proteins specialized for promoting or catalyzing a variety of molecular events. Pumps move specific organic solutes and inorganic ions across the membrane against a concentration gradient; energy transducers convert one form of energy into another, and receptors on the plasma membrane sense extracellular signals. These ideas will be reviewed in this unit and studied in more depth in Unit 12. Assignment: Nelson & Cox, pp. 343 - 345, 348 (start at section 10.2) - 349 (stop at "Some phospholipids have ether linked fatty acids"), 350, 354 - 355 ("sterols have four fused carbon rings"), 369 - 385 (stop at "caveolins. ..."), 389 - 391. 1. Given the total number of carbons, and the number and positions of double bonds, draw the structure of a straight-chain fatty acid (pp. 343 - 345).
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Unit 5 2 2. Representing the structure of a fatty acid as shown below, draw the structure of a phosphatidate (diacylglycerol 3-phosphate; p. 350). R-C-OH O a. What kind of linkage joins the fatty acids to the glycerol part of the molecule? b. What kind of linkage joins the phosphate to the glycerol part of the molecule? 3. Review the structures of the following (Fig. 10-8, p. 350). The reason why so many different lipids are found in membranes is still not clear. In eukaryotes the various internal membranes all have different lipid compositions, and none are formed from a single type of lipid. The shape
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This note was uploaded on 04/06/2008 for the course BIOBM 3300 taught by Professor Blankenshi during the Fall '08 term at Cornell.

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Unit5 - Unit 5 1 UNIT 5 MEMBRANES AND MEMBRANE PROTEINS...

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