Unit1 - Unit 1 1 UNIT 1 PART A: ORGANIC CHEMISTRY RELEVANT...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Unit 1 1 U NIT 1 P ART A: O RGANIC C HEMISTRY R ELEVANT TO B IOCHEMISTRY P ART B: P H P ART C: A MINO A CIDS AND P EPTIDES Note: The Quiz for this unit is written only. There is no oral quiz for Unit 1. The cellular concentration of most molecules is in the milli- or micro-molar range. We will therefore expect you to know the meaning of, and to be able to manipulate measurements with the following prefixes: nano (10 -9 , n) micro (10 -6 , μ ) milli (10 -3 , m)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Unit 1 2 P ART A: O RGANIC C HEMISTRY RELEVANT TO B IOCHEMISTRY Assignment: Nelson & Cox, pp. 13 - 14. Since organic chemistry is centrally relevant to biochemistry, we want everyone to be able to look at or write the structures of complex molecules with some understanding of the functional groups and types of bonds contained in them. This little review is a first step in that direction. 1. Write generalized structures for the functional groups shown in Fig. 1-15 (p. 14). 2. Write an equation for each of the following: (in each case include an arrow showing a nucleophilic attack by an appropriate atom on a carbonyl carbon (or phosphoryl phosphate). e.g . the formation of an ester from an acid and an alcohol [shown below]). RCOH R'OH R - C - OR' H O O + O + 2 •• a. The formation of an amide from an acid and ammonia b. The formation of an acid anhydride from two molecules of acetic acid c. The hydrolysis of an ester You do not need to worry about the catalysts or conditions necessary to make these equations practical in an organic chemistry laboratory, because we will be dealing with enzymatic catalysis. We do want you to know, however, that an ester is made up of an acid and an alcohol, etc.
Background image of page 2
Unit 1 3 P ART B: P H Assignment: Nelson & Cox, pp. 47 - 71 (skip pp. 56 - 59 section entitled "Solutes Affect the Colligative. ..."). 1. What is a hydrogen bond (Fig 2-1, p. 48)? a. What is required for a functional group to behave as a hydrogen bond donor (Fig. 2-3, p. 49)? b. What is required for a functional group to behave as a hydrogen bond acceptor (Fig. 2-3, p. 49)? 2. Define hydrophobic, hydrophilic, and amphipathic (pp. 50, 52). Given the molecular formula, be able to classify a molecule into one of these categories (Table 2-2, p. 51). 3. Use Fig 2-7 (p. 53) to describe a micelle. Name and describe the interactions that stabilize micelles. 4.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/06/2008 for the course BIOBM 3300 taught by Professor Blankenshi during the Fall '08 term at Cornell University (Engineering School).

Page1 / 9

Unit1 - Unit 1 1 UNIT 1 PART A: ORGANIC CHEMISTRY RELEVANT...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online