BacterialDisII121_OLS - Bacterial Pathogens of Humans Part...

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Bacterial Pathogens of Humans Part II Top 4 Bacterial Diseases Chosen by Students Acne Bacterial agent: Propionibacterium acnes 1. Member of normal microbiota 2. Pores blocked by excessive oil and dead cells (called comedos) P. acnes metabolizes oil substances produced inflammation of follicles Pustules/Papules Chronic inflammation Nodular cystic acne Pits and scars 3. Diet/chocolate not involved 4. Certain skin types that help trap oil and dead cells and male hormones (androgens) are involved Treatment: Drugs that reduce oil production (Accutane); drugs that target P. acnes (benzoyl peroxide, antibiotics); oral contraceptives (estrogen); and quite a few others Prevention: None (even the best efforts in skin care hygiene will not always prevent acne) Leprosy (Hansen’s Disease) Bacterial agent: Mycobacterium leprae 1. Two related chronic, progressive skin and nerve diseases (After infection with M. leprae , these diseases usually take 1 - 7 years to develop): Tuberculoid leprosy: Shallow, irregular skin lesions Some loss of sensation due to damage to nerves in affected areas Lepromatous leprosy: Serious, disfiguring disease (lumpy skin “lepromas”) Significant nerve damage (can lead to unrecognized injuries) 2.
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This note was uploaded on 02/13/2012 for the course MBI 121 taught by Professor Balish during the Fall '08 term at Miami University.

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BacterialDisII121_OLS - Bacterial Pathogens of Humans Part...

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