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Mic 428 Lecture 11-sample

Mic 428 Lecture 11-sample - Mic 4 2 8 Le c ture 1 1 R e g...

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Mic  428 -  Le c ture # 11 Re g ulatio n o f G e ne  Expre s s io n O utline The  c o m ple xity o f re g ulatio n. O ve rvie w o f re g ulatio n.  C o ns titutive  and induc ible  e nzym e s .  Majo r m o de s  o f re g ulatio n in the  c e ll: 1. C o ntro l o f e nzym e  ac tivity. Po s t trans latio nal c o ntro l. Requires review of Chapter 7 before coming to class.
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Mic  428 -  Le c ture # 11 Re g ulatio n o f G e ne  Expre s s io n O utline Fe e dbac k inhibitio n. Allo s te ric  re g ulatio n and rate -lim iting  e nzym e s . Type s  o f allo s te ric  re g ulatio n. Is o e nzym e s .  2. C o ntro l o f the  am o unt o f e nzym e  pre s e nt: trans c riptio nal  c o ntro l and trans latio nal c o ntro l (NEXT C LAS S ).
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C o m ple xity o f re g ulatio n Hundre ds  o f diffe re nt e nzym atic  re ac tio ns  happe ning   s im ultane o us ly. Ne e d to  re s po nd rapidly to  c hang e s  in the ir e nviro nm e nt. C o m plic ate d de ve lo pm e ntal pathways .
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S o m e  e nzym e s  are  ne e de d in the  s am e  am o unt  unde r any g ro wth c o nditio n.
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