lecture 21 W11 - Tips for doing well on exams III and IV:...

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Tips for doing well on exams III and IV: 1) Come to lecture!!! 2) Take discussion seriously!!! 3) Use lecture notes to understand the lecture material 4) Don’t let the book become a distraction 5) Go to someone’s office hours Cadigan office hours (in Nat. Sci. 3141) Wed 4-5pm Fri 1-3pm
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Today’s topics 1) Cytoplasmic transplantation to identify MPF 2) Regulation of the G2/M transition by MPF 3) How to interpret cartoons depicting molecular models in modern cell/molecular biology 4) Cell cycle control and cancer Lecture 21 (3/7/11) - Regulation of the cell cycle
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Molecules; Chemical bonds; Free energy Lipids Amino acids nucleotides carbohydrates membranes proteins Membrane transport Membrane proteins cytoskeleton enzymes DNA RNA Metabolism Sugar transport Electrolyte transport Kidney Nerve cells Transporters and pumps Receptors Cell-cell communication Chemical signaling development Replication transcription translation Glycolysis Fermentation Krebs cycle Photo- Synthesis & Calvin cycle Cell cycle Regulation of transcription biotechnology genomics Microbes Biology 172 flowchart (lecture 21) cancer
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Cell cycle Mitosis
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Cell-cycle length can vary greatly among cell types. G 1 phase is practically eliminated in rapidly dividing cells. Nondividing cells get permanently stuck in G 1 phase; this arrested stage is called the G 0 state. Injection of M-phase cytoplasm into an interphase cell causes the interphase nucleus to enter M phase. M-phase promoting factor (MPF) is present in the cytoplasm of M-phase cells and induces mitosis. MPF induces mitosis in all eukaryotes.
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Mitosis-phase (M-phase) cytoplasm into interphase cells. The interphase cytoplasm
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lecture 21 W11 - Tips for doing well on exams III and IV:...

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