Lecture 22 - 3) Once you have a polymer, how do you get a...

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Lecture 22 1) 1953 – Stanley Miller – Experiment to test that complex molecules could be formed spontaneously like in the early Earth. Nothing happened at first, but when he introduced an electrode, he found that after a week the liquid was a deep red, and there were 30 simple and complex molecules, 6 were amino acids, and something that was a part of DNA – basic building blocks of life. a) Experiment has been repeated, under different conditions 18 of the 20 amino acids have been produced. b) When the experiment was run with Carbon Monoxide, you don’t get any molecules. 2) 1996 Experiment – Test tubes with a small oglionucleotide, silica clay, and adenosine nucleotides. Incubate for a day, spin down tubes, clay collects at bottom, pour off supernatant. Due this over the course of 10 weeks, then run them out on a gel. a) Idea is that these clays catalyzed the formation of monomers.
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Unformatted text preview: 3) Once you have a polymer, how do you get a cell? a) Hypothesis is that some polymers aggregated and formed an environment that was different than the external environment. i) In the lab, can create liposomes – spontaneously form a sort of lipid bilayer, they eat smaller liposomes, selectively allow certain molecules in, also divide to form a sort of daughter cell. b) Need hereditary material so the characteristics can be passed on. DNA – RNA – Proteins i) DNA is capable of info storage, but they are not capable of catalytic activity. Proteins can experience exquisite catalytic activity, but they cant self replicate. ii) Probably original material was RNA. DNA is more stable than RNA. c) RNA is capable of storage and catalytic activity. Since RNA is single stranded, its 3D structure isn’t as limited as DNA. 4)...
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This note was uploaded on 02/09/2012 for the course BIOL 104 taught by Professor Smith during the Spring '09 term at Arkansas State.

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