19.4 - 19.4 Case 4 The Huntington's Disease Story: Finding...

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19.4 Case 4 – The Huntington’s Disease Story: Finding Genes by Mapping They first ask how researchers actually find the genes that are associated with certain traits? The answer is conceptually simple: you start off with a map of known sites in the genome and then look for correlations between one of those sites and the phenotype you’re looking for the actual gene you are looking for is probably close to this known site How was the Huntington’s disease gene found? o Huntington’s starts to show symptoms between the ages of 35 and 45. Some symptoms can be clumsiness, tics and weird movements o As it progresses the uncontrolled movement gets worse and worse and their personality and intelligence go away too and its eventually fatal o At first researchers thought that it was a genetic disease due to a single, autosomal dominant allele o Nancy Wexler started to lead the search for the gene, her mom had the disease o To start off the research they used something, what was it? Answer:
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This note was uploaded on 02/12/2012 for the course SCI 2341 taught by Professor Yates during the Spring '11 term at Alabama.

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19.4 - 19.4 Case 4 The Huntington's Disease Story: Finding...

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