4_CH7_1_APs (4) - CH 7: Nervous System Neurons and Synapses...

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CH 7: Nervous System Neurons and Synapses (pp 162-170) Neurons & supporting cells: REVIEW (pp152-162) Electrical Activity in Axons (pp 162-170) Ion Gating in Axons Action Potentials All or none law Coding for stimulus intensity Refractory periods Cable properties of neurons Conduction of Nerve Impulses Conduction in an unmyelinated axon Conduction in a myelinated axon
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Resting Membrane Potential (RMP) At rest, all cells have a negative internal charge (from large anions being  CELL: Low Na+ inside / high Na+ outside and  High K+ inside / low K+ outside . Difference in ion concentrations maintained by     (1) Na+/K+ pump (Na+ out, K+ in);    (2) membrane impermeable to Na+; but permeable to K+;     (3) electrochemical gradients. High negative charge inside attracts in  positively charged ions (K+). rapid changes in their permeability to ions: it is the ion movement across the  membrane that generates & conducts nerve impulses (APs).
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Fig 7.11 Electrical Activity in Axons Measured by placing one electrode inside cell & one outside
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1. Depolarization: occurs when MP becomes  more positive. 2. Hyperpolarization
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4_CH7_1_APs (4) - CH 7: Nervous System Neurons and Synapses...

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