chapter8 - Chapter 8 Nucleotides and Nucleic Acids Multiple...

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Chapter 8 Nucleotides and Nucleic Acids Multiple Choice Questions 1. Some basics Pages: 271-273 Difficulty: 1 Ans: E The compound that consists of ribose linked by an N -glycosidic bond to N-9 of adenine is: A) a deoxyribonucleoside. B) a purine nucleotide. C) a pyrimidine nucleotide. D) adenosine monophosphate. E) adenosine . 2. Some basics Page: 273 Difficulty: 1 Ans: E A major component of RNA but not of DNA is: A) adenine. B) cytosine. C) guanine. D) thymine. E) uracil . 3. Some basics Page: 273 Difficulty: 1 Ans: A The difference between a ribonucleotide and a deoxyribonucleotide is: A) a deoxyribonucleotide has an —H instead of an —OH at C-2. B) a deoxyribonucleotide has α configuration; ribonucleotide has the β configuration at C-1. C) a ribonucleotide has an extra —OH at C-4. D) a ribonucleotide has more structural flexibility than deoxyribonucleotide. E) a ribonucleotide is a pyranose, deoxyribonucleotide is a furanose. 4. Some basics Page: 273 Difficulty: 2 Ans: D Which one of the following is true of the pentoses found in nucleic acids? A) C-5 and C-1 of the pentose are joined to phosphate groups. B) C-5 of the pentose is joined to a nitrogenous base, and C-1 to a phosphate group. C) The bond that joins nitrogenous bases to pentoses is an O -glycosidic bond. D) The pentoses are always in the β -furanose forms. E) The straight-chain and ring forms undergo constant interconversion.
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Nucleotides and Nucleic Acids 5. Some basics Pages: 274-275 Difficulty: 2 Ans: E The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA: A) always link A with T and G with C. B) are susceptible to alkaline hydrolysis. C) are uncharged at neutral pH. D) form between the planar rings of adjacent bases. E) join the 3 ' hydroxyl of one nucleotide to the 5 ' hydroxyl of the next . 6. Some basics Pages: 274-275 Difficulty: 2 Ans: A The phosphodiester bond that joins adjacent nucleotides in DNA: A) associates ionically with metal ions, polyamines, and proteins. B) is positively charged. C) is susceptible to alkaline hydrolysis. D) Links C-2 of one base to C-3 of the next. E) links C-3 of deoxyribose to N-1 of thymine or cytosine. 7. Some basics Page: 275 Difficulty: 2 Ans: D The alkaline hydrolysis of RNA does not produce: A) 2 ' - AMP. B) 2 ' ,3 ' -cGMP. C) 2 ' -CMP. D) 3 ' ,5 ' -cAMP. E) 3 ' -UMP. 8. Some basics Page: 276 Difficulty: 2 Ans: B The DNA oligonucleotide abbreviated pATCGAC: A) has 7 phosphate groups. B) has a hydroxyl at its 3 ' end. C) has a phosphate on its 3 ' end. D) has an A at its 3 ' end. E) violates Chargaff's rules. 9. Some basics Page: 276 Difficulty: 2 Ans: D For the oligoribonucleotide pACGUAC: A) the nucleotide at the 3 ' end has a phosphate at its 3 ' hydroxyl.
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chapter8 - Chapter 8 Nucleotides and Nucleic Acids Multiple...

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