Barbour Lecture - Bioelectricity: Sensory Transduction and...

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1 September 15, 2010 Bioelectricity: Sensory Transduction and the Auditory System Dennis L. Barbour BME140 Department of Biomedical Engineering Washington University in St. Louis 2 Goals of Lecture • Introduce sensory systems • Provide examples of engineering principles in studying sensory coding • Motivate the learning process over the upcoming two years
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2 3 Bigger and Better Things Pillars of Knowledge BME 301 Math 132 Math 233 Math 217 ESE 317 Biol 2960 Biol 2970 Biol 3058 BME 140 CSE 131 BME 240 EP 310 Phys 117A Phys 118A ESE 230 High School 4 Outline • Sensory transduction – different modalities – receptive fields • Acoustics and vibrations –p r e s s u r e w a v e s – middle ear – signal processing –c o c h l e a r m e c h a n i c s • Biophysics and neural encoding –h a i r c e l l s –a u d i t o r y n e r v e • Cochlear Implant (i.e., “bionic ear”)
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3 5 Transduction Organs in Different Sensory Modalities Kandel, Schwartz and Jessell, 2000 6 Receptive Fields Purves, Sinauer Associates, Sunderland, MA, 1997
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4 7 Auditory Nerve Tuning Curve isorate contour “receptive field” Kandel, Schwartz and Jessell, 2000 8
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Barbour Lecture - Bioelectricity: Sensory Transduction and...

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