Moran Lecture - 9/28/2010 1 Neural Prosthetics BME 140:...

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Unformatted text preview: 9/28/2010 1 Neural Prosthetics BME 140: Moran Lecture Dobelle Visual Neuroprosthetic Robo-Rat: Somatosensory Neuroprosthetic Robo-Rat What does the brain do? Spinal Cord Injury 250,000 Americans with spinal cord injuries Approximately 11,000 i j i h new injuries occur each year in US. 9/28/2010 2 Motor Neuroprosthetics Powered Wheelchair Robotic Limbs Signal Detection Scalp Non-invasive EEG Single Units Epidural ECoG Skull Dura Cortex Non invasive Highly invasive Minimally invasive 9/28/2010 3 120 Time (ms) Firing Rate (Hz) 9/28/2010 4 9/28/2010 5 9/28/2010 6 Attitude Control in Motor Cortex Behavior paradigm: The center out + rotation task A representative M1 neuron modulated by hand orientation 1 2 (PD) r 2 =0.90 p=0.02 5-1000-500 500 1000 (ms) 6 DR158*** Cell A 3 4 7 8 1 2 (PD) r 2 =0.90 p=0.02 5-1000-500 500 1000 (ms) 6 DR158*** Cell A 3 4 7 8 9/28/2010 7 1 2 (PD) r 2 =0.90 p=0.02 5-1000-500 500 1000 (ms) 6 DR158*** Cell A 3 4 7 8 40 50 60 sec) DR477 CW CCW-180-120-60 60...
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Moran Lecture - 9/28/2010 1 Neural Prosthetics BME 140:...

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