Known Unknowns-The Amino Acids

Known Unknowns-The Amino Acids - A lanine, Ala, A V aline,...

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Amino Acids Codes Transmembrane (TM) domains do not have multiple charged residues in them. Sometimes single charged residues are tolerated. Sometimes a single Proline is tolerated. Underlined residues are common in TM domains Italicized residues are charged G lycine, Gly, G A lanine, Ala, A V aline, Val, V L eucine, Leu, L I soleucine, Ile, I M ethionine, Met, M F enylalanine (phenylalanine), Phe, F P roline, Pro, P S erine, Ser, S T hreonine, Thr, T C ysteine, Cys, C Asparagi N e, Asn, N Q utamine (glutamine), Gln, Q T Y rosine, Tyr, Y T W tophan (tryptophan), Trp, W Aspar D ic (aspartic) Acid, Asp, D Glu E tamic (glutamic) Acid, Glu, E H istidine, His, H Lysine, Lys, K A R ginine, Arg, R
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All hydrophobic (carbon side chains)
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Unformatted text preview: A lanine, Ala, A V aline, Val, V L eucine, Leu, L I soleucine, Ile, I A, V, L, I substitute for each other . A/V V/I L/I not as good Uncharged/hydrophobic Asparagi N e, Asn, N Q utamine (glutamine), Gln, Q N/Q substitute for each other . Polar S erine, Ser, S T hreonine, Thr, T S/T substitute for each other . T Y rosine, Tyr, Y T W tophan (tryptophan), Trp, W Sometimes Y/W substitute for each other Charged Aspar D ic (aspartic) Acid, Asp, D Glu E tamic (glutamic) Acid, Glu, E D/E substitute for each other . Lysine, Lys, K A R ginine, Arg, R K/R substitute for each other ....
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Known Unknowns-The Amino Acids - A lanine, Ala, A V aline,...

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