Lecture 9 Biol302 Spring 2011

Lecture 9 Biol302 Spring 2011 - Studying Segmentation...

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Studying Segmentation Mutants in Balanced Stocks
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Drosophila Development Each egg is surrounded by a chorion . The anterior end has two filaments to allow oxygen to enter the cell. Sperm enter through the micropyle at the anterior end.
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Early Drosophila Development It takes 1 day for the embryo to develop into a larva . The larva hatches, feeds, and sheds its skin twice. After 5 days, the larva becomes immobile and forms a pupa . During the pupal stage, cells in the imaginal discs differentiate into adult structures.
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Maternal Gene Activity in Development Materials transported into the egg during oogenesis play a major role in embryonic development.
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Maternal-Effect Genes Maternal-effect genes contribute to the formation of healthy eggs; effects of mutations in these genes may not affect the phenotype of the female making the eggs but may be seen in the next generation. A maternal-effect mutation causes a mutant phenotype in the offspring of a female with a mutant genotype.
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The dorsal Gene: Offspring of dl/dl Females are Dorsalized and Inviable
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Segmentation genes are required for segmentation along the anterior-posterior axis. They are classified into three groups based on embryonic mutant phenotypes. Gap genes
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Lecture 9 Biol302 Spring 2011 - Studying Segmentation...

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