Lecture 22 Spring Biol302

Lecture 22 Spring Biol302 - products, or to serve as animal...

Info iconThis preview shows pages 1–21. Sign up to view the full content.

View Full Document Right Arrow Icon
Production of Eukaryotic Proteins in Bacteria Human insulin, human growth hormone, and other valuable eukaryotic proteins can be produced economically in genetically engineered bacteria.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Expression of Human Growth Hormone in E. coli
Background image of page 2
Key Points Valuable proteins that could be isolated from eukaryotes only in small amounts and at great expense can now be produced in large quantities in genetically engineered bacteria. Proteins such as human insulin and human growth hormone are valuable pharmaceuticals used to treat diabetes and pituitary dwarfism, respectively.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Transgenic Animals Synthetic, modified, or other foreign genes can be introduced into animals and plants, and the resulting transgenic organisms can be used to study the function of the genes, for example, by insertional mutagenesis, to produce novel
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 12
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 14
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 16
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 18
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 20
Background image of page 21
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: products, or to serve as animal models for studies of inherited human diseases. Production of Transgenic Mice by DNA Injection into Eggs Transgenic Mice Expressing Human Growth Hormone Reverse Genetics: Dissecting Biological Processes by Inhibiting Gene Expression Reverse genetic approaches make use of known nucleotide sequences to devise procedures for inhibiting the expression of specific genes. Reverse Genetics Reverse genetic approaches use the nucleotide sequences of genes to devise procedures for isolating null mutations in them or shutting off their expression. The function of a gene often can be deduced by studying organisms lacking any functional product of the gene. Knockout Mice Production of Gene-targeted Embryonic Stem Cell Technology...
View Full Document

Page1 / 21

Lecture 22 Spring Biol302 - products, or to serve as animal...

This preview shows document pages 1 - 21. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online