transgenic_talk 2010 copy

transgenic_talk 2010 copy - Transgenic Transgenic: an...

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Transgenic Transgenic: an organism that has had DNA introduced into one or more of its cells artificially “transgenic”: DNA is integrated in a random fashion by injecting it into the pronucleus of a fertilized ovum Random (approx. . 10% disrupt an endogenous gene important for normal development) multiple copies
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Transgenic Transgenic: an organism that has had DNA introduced into one or more of its cells artificially “transgenic”: DNA is integrated in a random fashion by injecting it into the pronucleus of a fertilized ovum Random (approx. . 10% disrupt an endogenous gene important for normal development) multiple copies
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Transgenic production Transgenic mice are often generated to 1. characterize the ability of a promoter to direct tissue-specific gene expression e.g. a promoter can be attached to a reporter gene such as LacZ or GFP 2. examine the effects of overexpressing and misexpressing endogenous or foreign genes at specific times and locations in the animals
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Brinster's growth hormone mouse
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transgenic_talk 2010 copy - Transgenic Transgenic: an...

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