# 2010 - BME 403 Fall 2010 Respiratory Section Exam...

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BME 403 Fall 2010 Respiratory Section Exam Name__Solutions_________________ 100 points total, closed book, 80 min Scientific calculator required 1.(25) Mark True (T) or False (F) 1 point each (T )1.1 For a young normal subject all the ventilation and blood flow goes to compartments close to a ventilation perfusion ratio of 1.0 and in particular there is no blood flow to the unventilated compartment (shunt). (F )1.2 At 8000 feet altitude where the barometric pressure is 565 mm Hg the absolute maximum possible(infinite ventilation) arterial oxygen partial pressure breathing ambient air(FIO2=.21) at 20 deg C(PH2O=17.5 mm Hg) is 115 mm Hg( PH20 at 37 deg C = 47 mm Hg). .21*(565-47)=108.8 (T )1.3 Hypoventilation would be consistent with an arterial partial pressure of oxygen of 80 mm Hg. (F )1.4 A diver at 33 feet sea water depth in the feet up position would have due to the inverted pleural pressure gradient higher blood flow and ventilation in the top (apex) of the lungs. (T )1.5 In a climbing aircraft with an acceleration of 1 g the pleural pressure gradient in the lungs is doubled compared to flying at a constant altitude. (T )1.6 At high lung volumes pulmonary vascular resistance is high because capillaries are stretched and therefore narrowed. (F )1.7 By standing feet up (inverted) blood flow in the lungs is higher at the base than the apex. (F )1.8 Hypoxia would be expected to lead to an increase in pulmonary blood flow. (T )1.9 The phrenic nerve is responsible for contraction of the diaphragm. (T )1.10 The external intercostals muscles are inspiratory muscles. (T )1.11 For very large volume changes the lung volume at any given pressure during deflation is larger than during inflation. (T )1.12 Normal lungs inflated with saline are easier to distend than inflating with air. (T )1.13 Although in the upright posture the base of the lungs is relatively poorly expanded compared with the apex, it is better ventilated.

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(T )1.14 Arterial hypoxia of 80 mm Hg with arterial PaCO2 = 40 mm Hg in a normal person is expected to lead to almost no increase in ventilation. (T
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2010 - BME 403 Fall 2010 Respiratory Section Exam...

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