Grikscheit2

Grikscheit2 - Tissue Engineering the Gastrointestinal...

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Unformatted text preview: Tissue Engineering the Gastrointestinal Tract: Part II- Hurdles Tracy Grikscheit, MD Assistant Professor of Surgery Attending Surgeon Childrens Hospital Los Angeles Department of Surgery Keck School of Medicine University of Southern California What do you see as the hurdles to success Is the amount grown better than current options? What about function and storage options? Does this cross species- work for humans? Better cells Growth factors GMP sourcing Cellular mechanisms Experimental design TISSUE-ENGINEERED SMALL INTESTINE Experimental design Organoid Units on Polymer Implantation Intestine Biopsy Organoid Unit Isolation Engineered Intestine Intestinal epithelium Sala FG, Kunisaki SM, Ochoa ER, Vacanti J, Grikscheit TC. Tissue-Engineered Small Intestine and Stomach Form from Autologous Tissue in a Preclinical Large Animal Model. J Surg Res 156:205-212, 2009. Sala FG, Kunisaki SM, Ochoa ER, Vacanti J, Grikscheit TC. Tissue-Engineered Small Intestine and Stomach Form from Autologous Tissue in a Preclinical Large Animal Model. J Surg Res 156:205-212, 2009. J Surg Res 156:205-212, 2009....
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This note was uploaded on 02/15/2012 for the course BME 410 taught by Professor Han during the Fall '08 term at USC.

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Grikscheit2 - Tissue Engineering the Gastrointestinal...

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