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APK3110-Ch4-ExMetab_Spring+2012 (1)

APK3110-Ch4-ExMetab_Spring+2012 (1) - EXERCISE METABOLISM...

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EXERCISE METABOLISM Chapter 4
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Objectives 1. Define oxygen deficit and debt, EPOC and lactate threshold 2. Discuss explanations for rise in blood lactate concentration during incremental exercise 3. List the factors that regulate fuel selection during different types of exercise 4. Explain why fat metabolism is dependent on carbohydrate metabolism
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Resting Energy Expenditure At rest, ATP is produced almost 100% aerobically Oxygen consumption (VO 2 ) provides an index of aerobic ATP production (aerobic metabolism) During rest: 70kg person = 0.25 L/min VO 2 3.5 ml/kg/min Because oxygen is readily available at rest, pyruvate enters the Krebs cycle rather than being converted to lactate…so, blood lactate levels are low ( <1 mmol/L ) Acetyl-CoA Krebs Cycle
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