APK3110-Ch5-Hormones_Spring+12_part+A

APK3110-Ch5-Hormones_Spring+12_part+A - HORMONAL RESPONSES...

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HORMONAL RESPONSES TO EXERCISE Chapter 5
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Objectives Describe the general classification and function of hormones Describe the physiology of the principal “exercise hormones” Describe how hormones affect carbohydrate utilization during exercise
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Neuroendocrinology Blood glucose Calcium concentration Potassium concentration Sodium concentration Water concentration/volume Blood pressure pH Nervous System Endocrine System Slow, blood-born mechanisms of action Immediate, neuron-mediated mechanisms of action What controls the mixture of fuel used by the muscle? What stimulates adipose tissue to release more FFA? How does the liver know that there is a need to replace plasma glucose being used by the muscle? Etc…
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Signal Transduction The nervous system uses neurotransmitters and the endocrine system uses hormones as chemical messengers ( ligands ) that bind to specific proteins ( receptors ) Ligand-receptor interaction causes a response in the target cell called signal transduction
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Classes of Chemical Messengers The structure of a chemical messenger determines its mechanisms of synthesis release transport signal transduction The most important chemical characteristic is whether the messenger can dissolve in water or cross the plasma membrane (lipid bilayer) Lipophilic messengers lipid-soluble Cross membrane easily, don’t dissolve in water Lipophobic messengers water-soluble Don’t cross membrane, do dissolve in water
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This note was uploaded on 02/15/2012 for the course APK 3110C taught by Professor Dr.christou during the Spring '11 term at University of Florida.

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APK3110-Ch5-Hormones_Spring+12_part+A - HORMONAL RESPONSES...

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