Objectives •Describe the general classification and function of hormones •Describe the physiology of the principal “exercise hormones” •Describe how hormones affect carbohydrate utilization during exercise
Neuroendocrinology Blood glucose Calcium concentration Potassium concentration Sodium concentration Water concentration/volume Blood pressure pH Nervous System Endocrine System Slow, blood-born mechanisms of action Immediate, neuron-mediated mechanisms of action What controls the mixture of fuel used by the muscle? What stimulates adipose tissue to release more FFA? How does the liver know that there is a need to replace plasma glucose being used by the muscle? Etc…
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Signal Transduction •The nervous system uses neurotransmitters and the endocrine system uses hormones as chemical messengers (ligands) that bind to specific proteins (receptors) •Ligand-receptor interaction causes a response in the target cell called signal transduction