APK3110-Ch5-Hormones_Spring+12_part+B

APK3110-Ch5-Hormones_Spring+12_part+B - GLANDS AND THEIR...

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Unformatted text preview: GLANDS AND THEIR HORMONES Chapter 5 What stimulates hormone release? What happens during exercise? Hormones: Regulation and Action Hormones are secreted from endocrine glands Hypothalamus and pituitary glands Thyroid and parathyroid glands Adrenal glands Pancreas Testes and ovaries Hypothalamus Stimulates release of hormones from anterior pituitary gland (true gland) by using hormones or factors Provides hormones for release from posterior pituitary (neural tissue extending from hypothalamus) Growth Hormone Secreted from the anterior pituitary gland Stimulates release of insulin-like growth factors (IGFs) IGF-1 produced in muscle responsible for muscle hypertrophy Essential for normal growth of all tissues Stimulate amino acid uptake and protein synthesis Long bone growth Growth hormone spares plasma glucose Reduces the use of plasma glucose Increases gluconeogenesis in liver Increases mobilization of fatty acids from adipose tissue Growth Hormone and Performance A CLOSER LOOK 5.1 PG. 80 Once extracted from pituitary glands of cadavers for medical use in growth disorders (e.g., dwarfism) Once promoted as anti-aging drug Excess GH in adolescence: Gigantism Excess GH in adulthood: Acromegaly A Closer Look 5.1 Growth Hormone and Performance GH increases protein synthesis in muscle and long bone growth Used to treat childhood dwarfism Also used by athletes and elderly More adverse effects than benefits (diabetes, hyperlipidemia, arthritis, cardiomegaly, shortened life-span) No evidence that GH promotes strength gains Increases collagen synthesis in muscle, not contractile protein Difficult to detect usage by athletes Antidiuretic hormone (ADH) or vasopressin Released by posterior pituitary Reduces water loss from the body to maintain plasma volume Favors reabsorption of water from kidney tubules into capillaries to maintain body fluid Release stimulated by high osmolality (low water concentration) and low plasma volume Due to sweat loss without water replacement Increases during exercise >60% VO 2 max to maintain plasma volume Change in Plasma ADH Concentration During Exercise Figure 5.7 Figure 5....
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This note was uploaded on 02/15/2012 for the course APK 3110C taught by Professor Dr.christou during the Spring '11 term at University of Florida.

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APK3110-Ch5-Hormones_Spring+12_part+B - GLANDS AND THEIR...

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