PS 3 answers, prob 2 - 1. Rr 2. RY 3. RY 4. Rr 5. RY 6. RR...

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Problem 2. A rare recessive X-linked mutation has been found which is caused by a SNP in exon 1. This SNP causes a RFLP in which EcoRI will not cut the mutant fragment. EcoRI normally cuts to give two bands: 200 bp and 600 bp. a) Fill out the genotypes for each known individual and all possible genotypes for the unkown. Assume unrelated individuals do not carry the mutation and do not have the disease (must be homozygous dominant).
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Unformatted text preview: 1. Rr 2. RY 3. RY 4. Rr 5. RY 6. RR or Rr 7. rY 8. rY 9. RR or Rr b) Draw the appropriate bands on the gel for individuals whose genotypes are known and explain the possible bands for individuals of unknown genotypes according to possible genotypes. 6 and 8 can be RR (600 and 200) or Rr (all three bands) (1) (2) 1 2 3 4 5 6 7 8 9 800 bp 600 bp 200 bp Ladder 1 2 3 4 5 6 7 8 9...
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