PS 1 answers, prob 10 - Defective tail B) If you insert a...

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Problem 10. If you insert an extra nucleotide at position A, what will be the phenotype of an animal homozygous for this mutation? (Please do not invoke any obscure phenomena or concepts we have not talked about in class—these questions are just as straight-forward as they appear!) Defective tail, but otherwise wild-type If you insert a nucleotide at position C, what will be the homozygous phenotype? Wild-type If you insert a nucleotide at position D, what will be the homozygous phenotype? Infertile If you insert a nucleotide at position C, and take one away from position D, what will be the homozygous phenotype? Infertile If you insert a nucleotide at positions A and C, what will be the homozygous phenotype?
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Unformatted text preview: Defective tail B) If you insert a nucleotide at position A, how might you be able to suppress the mutant phenotype at position B? Remove a nucleotide at position B If you add two nucleotides at position B, name two distinct alterations you could make at position A that would suppress the phenotype. 1. Add a nucleotide at position A 2. Remove two nucleotides at position A C) You find that you can suppress a mutation at position D by removing a nucleotide at position E, but not by removing one at position F. What does this tell you about the structure of the Fertilin gene? The region between E and F is critical for function, but the region between D and E is not....
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This note was uploaded on 02/15/2012 for the course PMB 13 taught by Professor Freeling during the Spring '09 term at University of California, Berkeley.

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