ps3, prob 11 - Ob 1 Ob 2 Ob 3 Ob 4 Ob 5 WT 1 WT 2 WT 3 WT 4...

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Problem 11. You have found a recessive mutation in Drosophila that makes flies obese, but they can still mate. You decide to map this mutant with two markers you have found—A SNP that generates a RFLP and a microsatellite. You cross an obese fly that is homozygous at alleles of both the SNP and the microsatellite to a normal sized fly that is homozygous for different alleles of the RFLP and microsatellite (see gel below). You cross the resulting F1 animal back to its obese parent . You analyze 5 obese and 5 phenotypically wildtype flies for the microsatellite and RFLP, as shown below. WT parent Obese parent F1
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Unformatted text preview: Ob 1 Ob 2 Ob 3 Ob 4 Ob 5 WT 1 WT 2 WT 3 WT 4 WT 5 Micro-satellite RFLP A) Draw the missing bands for both the microsatellite and RFLP for the F1 individual B) Based on the data, what is the map distance between the gene that controls body weight and the microsatellite? C) What is the map distance between the body weight gene and the RFLP? D) Are the microsatellite and RFLP linked to each other? If so what is the map distance between them?...
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This note was uploaded on 02/15/2012 for the course PMB 13 taught by Professor Freeling during the Spring '09 term at University of California, Berkeley.

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