ps3, prob 2 - disease (must be homozygous dominant). 1. 2....

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Problem 2. A rare recessive X-linked mutation has been found which is caused by a SNP in exon 1. This SNP causes a RFLP in which EcoRI will not cut the mutant fragment. EcoRI normally cuts to give two bands: 200 bp and 600 bp. a) Fill out the genotypes for each known individual and all possible genotypes for the unkown. Assume unrelated individuals do not carry the mutation and do not have the
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Unformatted text preview: disease (must be homozygous dominant). 1. 2. 3. 4. 5. 6. 7. 8. 9. b) Draw the appropriate bands on the gel for individuals whose genotypes are known and explain the possible bands for individuals of unknown genotypes according to possible genotypes. 1 2 3 4 5 6 7 8 9 800 bp 600 bp 200 bp Ladder 1 2 3 4 5 6 7 8 9...
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This note was uploaded on 02/15/2012 for the course PMB 13 taught by Professor Freeling during the Spring '09 term at University of California, Berkeley.

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