ps2, probs 12+13 - E) Over time, the mosquito population...

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Problem 12. Malaria infects humans by first infecting mosquitoes, which then pass on the disease to humans. Some mosquitoes have a recessive allele of a gene that when homozygous confers resistance to malaria. Mosquitoes with this genotype do not pass malaria on to humans. In a certain population, 10,000 out of 100,000 mosquitoes were unable to transmit malaria. A) Assuming Hardy-Weinberg equilibrium, what is the frequency of the resistance allele? B) What is the frequency of the non-resistance allele? C) Of the 100,000 mosquitoes, how many are expected to be carriers of the resistance allele (heterozygous)? The local government decides to exterminate the existing population -- and brings the population down to 10,000, but introduces 10,000 new mosquitoes bred in a lab, all of which are homozygous for the resistance allele. D) What is the frequency of the resistance allele now?
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Unformatted text preview: E) Over time, the mosquito population grew back to its natural size of 100,000. Assume there was no difference in fitness between the two alleles of the resistance gene. How many mosquitoes are expected to be resistant to malaria? F) If it turned out that being homozygous for the resistance allele caused mosquitoes to become partially sterile, do you predict a change in the frequency of alleles in the population? If so, which allele would increase in frequency? Problem 13. Vampire fang length is determined by incomplete dominance in two alleles of the caninula gene: C L C L : Long fangs C L C S : Intermediate fangs C S C S : Short fangs In a population of 1,000 vampires, 450 have long fangs, 50 have short fangs, and 500 have intermediate fangs. A) Determine the frequency of each allele. B) Are the allele frequencies maintained at Hardy-Weinberg equilibrium? How do you know?...
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This note was uploaded on 02/15/2012 for the course PMB 13 taught by Professor Freeling during the Spring '09 term at University of California, Berkeley.

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