Test 4 - Chapter 17-Stimulants Ease depression Induce...

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Chapter 17: -Stimulants Ease depression Induce euphoria Increase alertness Suppress appetite Banish fatigue Paradoxically: Some stimulants have been shown to calm some forms of hyperactivity Four subgroups: -Amphetamines and cocaine (Considered prototypes of stimulants) -Xanthines or methylxanthines (Caffeine, theobromine and theophylline): Fairly mild stimulants -Convulsants (Metrazol or strychnine) -Antidepressants Amphetamine: -Entered medical use as a treatment for asthma, narcolepsy, depression and hyperactivity in children and appetite suppressants -Unlike cocaine, amphetamine is well absorbed on the oral route, and can last up to 7 hours -Methamphetamine the methylated dl-form produces effects similar to the d- amphetamine form -Usually prepared with sulfuric acid -Orally: effects begin within 30 min and peak within 2-3 hours -IV: onset is 5 min -Lipid soluble -Release newly synthesized DA and NE from pre-synaptic terminals -Release larger quantities than usual at the synapse -Block reuptake at synapse
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Test 4 - Chapter 17-Stimulants Ease depression Induce...

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